‘Charulatha’ is the story of two conjoined twins named Charu & Latha -both played by Priyamani. One day, Charu and Latha goes to music classes to learn violin but was rejected by the master as he feels that they can’t play tough tunes as it may injure them. Both Charu and Latha prove their mettle and impress the master and starts learning violin. In the mean time, Charu slowly gets attracted to her classmate Ravi and eventually falls in love with him. This didn’t go well with Latha who also loves Ravi and as a result, troubles slowly start developing between them.  Suddenly, Latha dies under mysterious circumstances and becomes a ghost thus threatening Charu. What happens next? Can Charu get rid of the ghost of Latha and will she be able to marry Ravi has to be watched on screen.