The story begins with a series of seemingly unconnected events, all over the globe. In Uzbekistan, an ex-KGB officer is murdered. In Cape Town, a group of international business tycoons discuss a rumor that the dead KGB officer had a nuclear suitcase bomb hidden away. In Moscow, an Indian secret agent is exposed. The agent is shot dead while trying to send a code red message to India. In India, the head of RAW sees the incomplete message. All it contains is a number 242. Enter Agent Vinod. 

Vinod [Saif Ali Khan] is the kind of agent who first kicks the door open and then finds out what's behind it. His unconventional approach puts him in perilous circumstances, but he manages to get the decisive leads. Vinod is sent to Moscow to investigate why his colleague was killed. Vinod finds out that a Russian money launderer Abu Nazar [Ram Kapoor] has sent US$ 50 million to a contact in Morocco, for an operation against India. 

Vinod leaves for Morocco, where he meets an elderly Mafiosi Kazan [Prem Chopra] and the beautiful but mysterious Dr Ruby [Kareena Kapoor]. A series of twists and turns take Vinod across the globe from Marakkesh to Riga, Karachi to Delhi and finally, London. Where he discovers the ultimate conspiracy.